Erectile Dysfunction & Sexual Health

Penile Injections: Home Guide

Penile Injections: Home Guide

Video walkthrough

I walk through vial handling, sterile preparation, injection sites, and technique. Always use the dose you were prescribed. Open on YouTube

Supplies and storage

Trimix must be stored refrigerated at 36°F to 46°F. Use a 29G or 30G 1/2-inch insulin syringe.

Step by step

1. Preparation: Clean the vial top with alcohol swab and draw prescribed dose.

2. Safe Injection Zones: Inject strictly into the lateral shaft at the 10:00 or 2:00 clock position. Avoid the 12:00 dorsal midline and 6:00 ventral urethra.

3. Administration: Insert needle perpendicular (90 degrees). Depress plunger, remove needle, and hold firm pressure for 3-5 minutes.

If an erection lasts too long

Erections typically last 30 to 60 minutes. If erection persists past 3 hours, take oral pseudoephedrine (Sudafed). If erection reaches 4 hours, contact the clinic or emergency room immediately.

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Written and reviewed by Shervin Badkhshan, MD · Last reviewed

November 2026

Your results and questions

Your actual test results, visit notes, and messages with your care team are in your patient portal, the same one you use to book visits. Send questions through the portal or call the office at (516) 535-1900. For anything urgent, call the office or go to the nearest emergency room.